Preheat oven to 375. In large saucepan, boil pasta in water 10 minutes, stirring often, until al dente. Drain. Rinse with cold water. In 1-quart casserole dish, treated with nonstick cooking spray, combine Cheddar cheese and macaroni.
In blender, puree cottage cheese, milk, eggs, pepper sauce and 1 teaspoon mustard. Pour over macaroni. Stir lightly to distribute. In cup, mix bread crumbs with remaining one teaspoon mustard. Sprinkle over casserole. Bake 20 minutes. Serves four.
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